Twin-scroll, VNT, sequential, you name it... none of it gets rid of turbo lag. The real question is what kind of "lag" and how does it impact the driver? For day-to-day it might be an annoyance to some and a thrill (as the torque builds) to others. It's really only a "problem/danger" at the limit, however, DCT is a huge help here as it helps maintain load, reducing transitions and thus unsettling the car.
That's not to say that it can't happen... for example... going too fast through a sweeper one might depress the pedal a bit much, reducing load which has a snowball effect in reducing exhaust gas velocity, which reduces plenum pressure, etc etc... weight transfers forward, rear tires lose traction... you get the point.
The rest is a reply to
@MickOpalak
Agree about "stressed" however. The V6 is near its limit... the M139 isn't. The 2GR-FE was originally built for the Camry and made ~270hp. The supercharging/tuning takes the engine well past its designed point, thus increasing stress. For example, according to JUBU Performance, who have tons of experience tuning the engine both for street cars and race cars:
"No more engine damages by "breaking" the piston webs between the 1st and 2nd piston ring (possible with original pistons at power outputs higher than 430 hp)"
Source:
https://www.jubu-performance.com/en/tuning/part-jubu_exige__evora__3eleven_500_leistungskit-1926
I don't know what the limit of the M139 engine is, but it's a fully built forged-internals engine from the factory and these companies over-engineer (it's why Lotus gets ~400hp out of the V6 reliably). The engine takes more abuse in the form of boost pressure, but it's built to handle it and more. There are also ways of improving performance via efficiency rather than boost pressure.
P.S. A few mods within the V6 and it'll easily handle more power than the I4... so physics still applies, no replacement for displacement, I'm only talking about their 'state' out of the box.